Methods and pharmaceutical compositions for gnrh-i and...

Details Methods and pharmaceutical compositions for gnrh-i and... Methods and pharmaceutical compositions for gnrh-i and...

A - Human Necessities

61

K

A61K 39/00 (2006.01) A61K 38/08 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07H 21/04 (2006.01) A01N 65/00 (2006.01)

Patent

CA 2473890

Methods and compositions comprising GnRH-I and GnRH-II, GnRH-I and GnRH-II antibodies, anti-receptor antibodies, polynucleotide c onstructs and GnRH-I and GnRH-II analogs for immune enhancement and suppression, prevention and treatment of diseases and conditions characterized by abnormal T-cell activity, treatment of viral and prion-related diseases, and treatment of T- cell related neoplastic diseases are disclosed.

Cette invention a trait à des compositions contenant les GnRH-I et GnRH-II, à des anticorps des GnRH-I et GnRH-II, à des anticorps anti-récepteur des GnRH-I et GnRH-II, à des produits de recombinaison polynucléotidiques ainsi qu'à des analogues des GnRH-I et GnRH-II, aux fins de l'amélioration de la réponse immunitaire ainsi que de la suppression, de la prévention et du traitement de maladies et d'états pathologiques se caractérisant par une activité anormale des lymphocytes T. Ces substances servent également au traitement de maladies virales et de maladies associées aux prions ainsi qu'à celui de maladies néoplasiques associées aux lymphocytes T.

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