C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/00 (2006.01) A61K 49/00 (2006.01) C12Q 1/34 (2006.01) C12Q 1/37 (2006.01) C12Q 1/68 (2006.01) G01N 1/34 (2006.01) G01N 30/72 (2006.01) G01N 30/86 (2006.01) G01N 33/48 (2006.01) C40B 30/08 (2006.01)
Patent
CA 2754072
The present invention relates to methods and products associated with in vivo enzyme profiling. In particular, the invention relates to methods of in vivo processing of exogenous molecules followed by detection of signature molecules as representative of the presence of active enzymes associated with diseases or conditions. The invention also relates to products, kits, and databases for use in the methods of the invention.
La présente invention concerne des procédés et des produits associés à l'établissement d'un profil enzymatique in vivo. L'invention concerne en particulier des procédés permettant le traitement in vivo de molécules exogènes suivi par la détection de molécules de signature considérées comme représentatives de la présence d'enzymes actives associées à certaines maladies ou certains états pathologiques. L'invention concerne également des produits, des trousses et des bases de données destinés à être utilisés pour les procédés de l'invention.
Bhatia Sangeeta N.
Kwong Gabriel
von Maltzahn Geoffrey A.
Massachusetts Institute Of Technology
Smart & Biggar
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