C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/18 (2006.01) A61K 39/12 (2006.01) C07K 16/10 (2006.01) C07K 19/00 (2006.01) C12N 15/40 (2006.01) C12N 15/62 (2006.01) C12N 15/63 (2006.01)
Patent
CA 2630629
The invention relates to the pharmaceutical industry and describes a conserved area of the surface of the E protein, which can be used in the development of broad spectrum molecules which can be used in the prevention and/or treatment of infections caused by dengue virus 1-4 and other flaviviruses. The invention also relates to chimeric proteins which are intended for use as vaccines and for the prophylactic and/or therapeutic treatment of the four serotypes of dengue virus and other flaviviruses.
Cette invention en rapport avec l'industrie pharmaceutique décrit une zone conservée de la surface de la protéine E, pouvant être utilisée dans le développement de molécules à large spectre utiles dans la prévention et/ou le traitement des infections par le virus de la dengue 1-4 et autres flavivirus. Elle concerne, en outre, des protéines chimériques utilisées en tant que vaccins et traitement prophylactique ou thérapeutique contre les quatre sérotypes du virus de la dengue et autres flavivirus.
Ayala Avila Marta
Chinea Santiago Glay
Fleitas Salazar Noralvis
Gavilondo Cowley Jorge Victor
Gil Valdes Jeovanis
Centro de Ingenieria Genetica Y. Biotecnologia
Deeth Williams Wall Llp
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