Methods and reagents for gamma-globin typing

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01) C07H 21/00 (2006.01)

Patent

CA 2066906

Abstract Methods and reagents for determining an individual's genotype at the G.gamma.-globin locus with respect to a set of three alleles using sequence-specific oligonucleotide probes enable one to type samples from a variety of sources, including samples comprising RNA or cDNA templates, and can be applied to nucleic acids in which a target region spanning the polymorphism has first been amplified. This three- allele system facilitates typing tissue for determining individual identity and has application in the field of forensic science.

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