Methods and reagents for identifying modulators of neuronal...

Details Methods and reagents for identifying modulators of neuronal... Methods and reagents for identifying modulators of neuronal...

G - Physics

01

N

G01N 33/50 (2006.01) C12N 15/86 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2301795

The invention provides assays for modulators of neuronal apoptosis. The assays include measurement of the levels of p53, Bad, Bax, p21, p27 and phosphorylated Rb in neurons which have been induced to undergo apoptosis.

L'invention concerne des dosages permettant d'identifier les modulateurs de l'apoptose neuronale. Ces dosages consistent à mesurer les taux de p53, Bad, Bax, p21, p27 et Rb phosphorylé dans les neurones dans lesquels on a induit une apoptose.

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