Methods and reagents for inhibiting cell proliferation

Details Methods and reagents for inhibiting cell proliferation Methods and reagents for inhibiting cell proliferation

C - Chemistry, Metallurgy

07

H

C07H 21/02 (2006.01) A61K 31/713 (2006.01) A61K 48/00 (2006.01) A61P 35/00 (2006.01) C07H 21/00 (2006.01) C12N 15/54 (2006.01)

Patent

CA 2512492

Methods and reagents for reducing expression of proteins involved in intracellular signalling are disclosed. Specifically, siRNA sequences are provided for reducing expression of Src, stat3, and c-myc gene products. Combination treatments are disclosed for inhibiting cell proliferative pathways, and for reducing tumor growth in breast and colon cancer.

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