Methods and reagents for performing ion-capture digoxin assays

G - Physics – 01 – N

Patent

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G01N 33/546 (2006.01) G01N 33/532 (2006.01) G01N 33/538 (2006.01) G01N 33/543 (2006.01) G01N 33/544 (2006.01) G01N 33/545 (2006.01) G01N 33/569 (2006.01) G01N 33/574 (2006.01) G01N 33/58 (2006.01) G01N 33/74 (2006.01) G01N 33/76 (2006.01) G01N 33/94 (2006.01)

Patent

CA 2110296

2110296 9221975 PCTABS00017 The present invention includes novel digoxin assays employing a capture reagent, involving a first binding member conjugated to a polymeric anion substance, and a solid phase material containing a reaction site comprising a polymeric cation substance having a nitrogen content of at least about two percent. A test sample suspected of containing the analyte of interest may be contacted with the capture reagent to form a charged capture reagent/analyte complex. The complex is then contacted to the oppositely charged solid phase to attract, attach, and immobilize the capture reagent/analyte complex.

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