Methods and systems for detecting and/or sorting targets

Details Methods and systems for detecting and/or sorting targets Methods and systems for detecting and/or sorting targets

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2659745

Provided herein are methods and systems for detecting' and/or sorting targets in a samp.le based on the combined use of polynucleotide-encoded protein and- substrate polynucleotides. The polyhucleotide-encoded protein is comprised of a protein that specifically binds to a predetermined target and of an encoding polynucleotide that specifically binds to a substrate polynucleotide, wherein the substrate polynucleotide is attached to a substrate.

L'invention concerne des procédés et des systèmes qui sont destinés à détecter et/ou à trier des cibles dans un échantillon, et qui sont basés sur l'utilisation combinée d'une protéine codée par un polynucléotide et de polynucléotides de substrat. La protéine codée par un polynucléotide est constituée d'une protéine qui se lie spécifiquement à une cible prédéterminée et d'un polynucléotide codant qui se lie spécifiquement à un polynucléotide de substrat, le polynucléotide de substrat étant fixé à un substrat.

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