Methods and systems for the delivery of corticosteroids...

A - Human Necessities – 61 – K

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A61K 31/724 (2006.01) A61K 31/573 (2006.01)

Patent

CA 2634398

The present invention relates to methods and systems for the delivery of a corticosteroid comprising (1) an inhalable aqueous mixture comprising a corticosteroid and a solubility enhancer and (2) an inhalable nebulizer, wherein the delivery of the aqueous mixture comprising the corticosteroid by the nebulizer results in an enhanced pharmacokinetic profile of the corticosteroid as compared to conventional inhalable therapies.

La présente invention concerne des méthodes et des systèmes d'administration d'un corticostéroïde, lesquels systèmes comprennent (1) un mélange aqueux inhalable, composé d'un corticostéroïde et d'un agent améliorant la solubilité, et (2) un nébuliseur pour inhalation, l'administration du mélange aqueux contenant le corticostéroïde au moyen du nébuliseur permettant d'obtenir un meilleur profil pharmacocinétique du corticostéroïde par rapport à des traitements par inhalation classiques.

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