Methods and systems for treating restenosis sites using...

A - Human Necessities – 61 – N

Patent

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A61N 1/05 (2006.01) A61M 31/00 (2006.01) A61N 1/28 (2006.01) A61N 1/30 (2006.01)

Patent

CA 2612536

A system is provided for reducing restenosis. A catheter apparatus is provided with at least first and second mono-polar electrodes positioned at an inflatable balloon. The balloon is sized to be positioned and expanded at a restenosis site. A voltage pulse generator is coupled to the first and second mono-polar electrodes. The voltage pulse generator is configured to apply an electric field, in a controlled manner, to the restenosis site in an amount sufficient to produce electroporation of the restenosis site, and below an amount that causes thermal damage to the restenosis site.

L'invention concerne un système de réduction de la resténose. Un dispositif à cathéter comprend au moins des première et seconde électrodes monopolaires placées dans un ballonnet gonflable. Le ballonnet est dimensionné pour être placé et dilaté dans le site de resténose. Un générateur de décharge électrique est couplé aux première et seconde électrodes monopolaires. Le générateur de décharge électrique et configuré pour appliquer de manière contrôlée, à la zone de resténose, un champ électrique suffisant pour produire l'électroporation de la zone de resténose mais inférieur à un certain seuil au-delà duquel la zone de resténose risque de subir des dommages thermiques.

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