Methods and therapies for treating inflammatory conditions...

Details Methods and therapies for treating inflammatory conditions... Methods and therapies for treating inflammatory conditions...

A - Human Necessities

61

K

A61K 51/00 (2006.01) A61M 36/14 (2006.01) C07K 16/00 (2006.01)

Patent

CA 2623554

Compositions and methods for treating and imaging vulnerable plaque and other inflammatory conditions in a patient rely on the delivery of conversion electron-emitting sources and other radionuclides to regions of exposed collagen in the vasculature or other body lumens. The conversion electron- emitting sources or other radionuclides are coupled to a collagen-binding substance and administered to the vasculature or other body lumen to permit binding for imaging and/or therapeutic purposes.

La présente invention a trait à des compositions et des procédés pour le traitement et l'imagerie de la plaque vulnérable et d'autres conditions inflammatoires chez un patient grâce l'administration de sources d'émission électronique de conversion et d'autres radionucléides à des régions de collagène exposé dans le système vasculaire ou d'autres vaisseaux corporels. Les sources d'émission électronique de conversion ou d'autres radionucléides sont couplées à une substance de liaison au collagène et administrées au système vasculaire ou autre vaisseau corporel pour permettre la liaison à des fins d'imagerie et/ou thérapeutiques.

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