Methods, compositions, and automated systems for separating...

B - Operations – Transporting – 01 – D

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B01D 57/02 (2006.01) C12N 5/07 (2010.01) C12N 5/078 (2010.01) C12N 5/09 (2010.01) C12M 1/12 (2006.01) C12M 3/06 (2006.01) C12N 1/00 (2006.01) C12Q 1/02 (2006.01) G01N 1/40 (2006.01) G01N 15/02 (2006.01) G01N 15/05 (2006.01) G01N 15/06 (2006.01)

Patent

CA 2462914

The present invention recognizes that diagnosis and prognosis of many conditions can depend on the enrichment of rare cells from a complex fluid sample. In particular, the enrichment of fetal cells from maternal samples, such as maternal blood samples, can greatly aid in the detection of fetal abnormalities or a variety of genetic conditions. In addition, the present invention recognizes that the enrichment of rare malignant cells from patient samples, can aid in diagnosis, prognosis, and development of therapeutic modalities for patients.

La présente invention concerne une méthode permettant de déterminer, si un diagnostic et un pronostic de plusieurs conditions peuvent dépendre de l'enrichissement de cellules rares à partir d'un échantillon de fluide complexe. Notamment, l'enrichissement de cellules foetales provenant d'échantillons maternels, tels que des échantillons sanguins, peuvent grandement assister la détection d'anormalités foetales ou d'une variété de conditions génétiques. En outre, cette invention a trait à une méthode permettant de reconnaître, si l'enrichissement de cellules malignes provenant d'échantillons d'un patient peut faciliter le diagnostic, le pronostic, et le développement de modalités thérapeutiques pour des patients.

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