Methods, compositions and kits for the detection and...

Details Methods, compositions and kits for the detection and... Methods, compositions and kits for the detection and...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C07H 21/04 (2006.01) C12P 19/34 (2006.01)

Patent

CA 2520512

Compositions and methods for the diagnosis of lung cancer are disclosed. Such methods are useful to detect early tumors or provide adequate stage/grade information or tumor specificity. Compositions may comprise one or more lung tumor proteins, immunogenic portions thereof, or polynucleotides that encode such portions. Such compositions may be used, for example, to improve lung cancer diagnosis and prognosis and potentially differentiate between NSCLC and SCLC.

L'invention concerne des compositions et des méthodes pour le diagnostic d'un cancer du poumon. De telles méthodes sont utiles pour détecter précocement des tumeurs ou pour fournir des informations de stade appropriées ou de spécificité tumorale. Les compositions de l'invention peuvent comprendre une ou plusieurs protéines tumorales de poumon, des parties immunogéniques de celles-ci, ou des polynucléotides codant de telles parties. De telles compositions peuvent être utilisées, par exemple, pour améliorer le diagnostic et le pronostic de cancer du poumon et éventuellement pour effectuer une distinction entre NSCLC et SCLC.

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