Methods, compounds, compositions and vehicles for delivering...

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 309/15 (2006.01) A61K 31/185 (2006.01) A61K 31/395 (2006.01) A61P 25/00 (2006.01) A61P 25/28 (2006.01) C07C 309/14 (2006.01) C07D 207/16 (2006.01) C07D 209/16 (2006.01) C07D 217/24 (2006.01) C07D 233/64 (2006.01) C07D 291/02 (2006.01) C07D 317/40 (2006.01) C07D 333/24 (2006.01) C07H 7/02 (2006.01) C07H 15/02 (2006.01) C07J 41/00 (2006.01)

Patent

CA 2666246

The invention relates to methods, compounds, compositions and vehicles for delivering 3-amino-1 -propanesulfonic acid (3APS) in a subject, preferably a human subject. The invention encompasses compounds that will yield or generate 3APS, either in vitro or in vivo. Preferred compounds include amino acid prodrugs of 3APS for use, including but not limited to, the prevention and treatment of Alzheimer's disease.

L'invention concerne des procédés, des composés, des compositions et des véhicules permettant l'apport d'acide 3-amino-1-propane sulfonique (3APS) à un sujet, de préférence à un sujet humain. L'invention comprend des composés qui produiront ou généreront du 3APS, in vitro ou in vivo. Les composés préférés comprennent des promédicaments du 3APS à base d'aminoacides, utilisés notamment, mais sans y être limités, pour la prévention et le traitement de la maladie d'Alzheimer.

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