Methods, devices, and preparations for intervertebral disc...

A - Human Necessities – 61 – F

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A61F 2/44 (2006.01) A61K 38/39 (2006.01) A61L 27/24 (2006.01) A61L 27/50 (2006.01) A61L 31/04 (2006.01)

Patent

CA 2482309

A therapeutic method for treating mammalian intervertebral discs (30). A preparation of cross-linked collagen (39) is injected under pressure into the intradiscal space. The intervertebral distance in injected discs is immediately increased by the treatment. At least some mechanical properties of the treated vertebral column are preserved or partially restored. The method may be used to relieve back pain in patients, to increase patient height and to stabilized the spinal column. The therapeutic method may result in at least a partial regeneration of the nucleus pulposus (34), and/or development of cartilaginous or fibrocartilaginous tissues or dense fibrous tissues.

L'invention concerne une méthode thérapeutique de traitement des disques intervertébraux chez un mammifère. Une préparation de collagène réticulé est injectée sous pression dans l'espace intervertébral. La distance entre les vertèbres ayant reçu l'injection est augmentée immédiatement par le traitement. Au moins quelques propriétés mécaniques de la colonne vertébrale traitée sont préservées ou partiellement rétablies. Cette méthode peut être utilisée pour soulager une dorsalgie chez des patients, pour augmenter la taille d'un patient ou pour stabiliser la colonne vertébrale. La méthode thérapeutique de l'invention peut donner comme résultat au moins une régénération partielle du nucleus pulposus, et/ou le développement de tissus cartilagineux ou fibrocartilagineux ou de tissus fibreux denses.

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