Methods for accelerating bone and cartilage growth and repair

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/08 (2006.01) A61K 38/18 (2006.01) A61K 38/30 (2006.01) C07K 7/14 (2006.01) A61K 35/12 (2006.01) A61K 38/00 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2328871

The present invention provides improved methods, kits, and compositions for enhancing bone, cartilage and cartilage repair, bone and prosthesis implantation, and attachment and fixation of cartilage and cartilage to bone or other tissues, and chondrocyte proliferation comprising the administration of an effective amount of angiotensinogen, angiotensin I (AI), AI analogues, AI fragments and analogues thereof, angiotensin II (AII), AII analogues, AII fragments or analogues thereof or AII AT2 type 2 receptor agonists.

La présente invention concerne de nouveaux procédés, kits et compositions qui permettent d'améliorer la réparation des os et des cartilages, l'implantation d'os et de prothèse et l'accrochage et la fixation de cartilage sur des os ou d'autres tissus, ainsi que la prolifération de chondrocytes qui consiste à administrer une quantité efficace d'angiotensinogène, d'angiotensine I (AI), d'analogues AI, de fragments AI et d'analogues de ces derniers, d'angiotensine II (AII), d'analogues AII,de fragments AII ou d'analogues de ces derniers ou des agonistes du récepteur AII AT¿2? du type 2.

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