A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/00 (2006.01) A61K 38/39 (2006.01) A61K 38/48 (2006.01)
Patent
CA 2388918
The present invention provides compositions and methods for the treatment of diseases associated with the abnormal growth of cells, and more specifically cancer. The compositions and methods of the present invention provide a decreased dosage of chemotherapeutic and antiangionic agents. In particular, the present invention provides methods of administering low doses of endostatin protein. Also included are methods of antiangiogenic scheduling of one or more therapeutic agents.
La présente invention concerne des compositions et des méthodes destinées au traitement de maladies associées à la multiplication anormale des cellules et plus particulièrement du cancer. Les compositions et les méthodes de la présente invention utilisent des doses décroissantes d'agents chimiothérapeutiques et antiangiogéniques. En particulier, la présente invention concerne des méthodes permettant d'administrer de faibles doses d'endostatine. L'invention concerne également des méthodes de schématisation antiangiogénique d'un ou plusieurs agents thérapeutiques.
Browder Timothy
Fogler William E.
Folkman M. Judah
Kisker Oliver
O'reilly Michael S.
Browder Timothy
Entremed Inc.
Finlayson & Singlehurst
Fogler William E.
Folkman M. Judah
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