C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/00 (2006.01) C12N 5/00 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01)
Patent
CA 2656551
Methods as described herein relate to altering the potential infectivity of a cell or cells. Included are methods for altering DNA of non-terminally differentiated cells in locations that inhibit the function of at least one CCR5 gene relative to an unaltered version of the gene and providing stimulus for differentiation of the altered cell.
La présente invention concerne des procédés permettant de modifier l'infectiosité potentielle d'une cellule ou de cellules. L'invention concerne des procédés destinés à modifier l'ADN de cellules différenciées de manière non définitive dans des emplacements qui inhibent la fonction d'au moins un gène CCR5 par rapport à une version non modifiée du gène, et à appliquer un stimulus entraînant la différenciation de la cellule modifiée.
Bangera Mahalaxmi G.
Hood Leroy E.
Hyde Roderick A.
Ishikawa Muriel Y.
Jung Edward K. Y.
Borden Ladner Gervais Llp
Searete Llc
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