Methods for altering protein production rates

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/117 (2010.01) C12N 15/113 (2010.01) A01K 67/027 (2006.01) C07H 21/02 (2006.01) C12N 15/00 (2006.01) C12N 15/85 (2006.01) C12P 21/00 (2006.01) C12P 21/08 (2006.01)

Patent

CA 2561702

Methods for altering the cellular secretion rate of a protein, such as an antibody and the altered cells produced by the method are disclosed. The methods and altered cells are useful for producing high levels of proteins for therapeutic, diagnostic or research purposes.

Procédés permettant de modifier le taux de sécrétion cellulaire d'une protéine, telle qu'un anticorps, et cellules modifiées produites selon ledit procédé. Lesdits procédés et cellules modifiées sont utiles pour produire des quantités élevées de protéines à des fins thérapeutiques, diagnostiques ou de recherche.

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