Methods for amyloid removal using anti-amyloid antibodies

Details Methods for amyloid removal using anti-amyloid antibodies Methods for amyloid removal using anti-amyloid antibodies

C - Chemistry, Metallurgy

07

K

C07K 16/18 (2006.01) A61K 39/395 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2325600

Methods and related immunoglobulin peptides and fragments thereof are disclosed that enhance the cell-mediated immune response of a patient to deposits of amyloid fibrils. These methods exploit the opsonizing effect of antibodies directed toward amyloid material or its component parts.

On décrit des procédés et des peptides d'immunoglobuline associés ainsi que leurs fragments qui activent la réponse immunitaire à médiation cellulaire aux dépôts de fibrilles amyloïdes chez un patient. Les procédés exploitent l'effet opsonisant des anticorps dirigés contre la substance amyloïde ou ses éléments constitutifs.

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