Methods for analysis of nucleic acid methylation status and...

C - Chemistry – Metallurgy – 12 – P

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C12P 19/34 (2006.01) C07H 21/00 (2006.01) C12Q 1/68 (2006.01) C40B 30/04 (2006.01) G01N 33/58 (2006.01)

Patent

CA 2552007

The invention relates to methods for analysis of nucleic acid methylation status, and fragmentation and/or labeling and/or immobilization of nucleic acids. More particularly, the invention relates to methods for fragmentation and/or labeling and/or immobilization of nucleic acids comprising labeling and/or cleavage and/or immobilization at abasic sites.

L'invention concerne des méthodes qui permettent d'analyser l'état de méthylation d'acides nucléiques et de fragmenter et/ou de marquer et/ou d'immobiliser des acides nucléiques. D'une manière plus spécifique, l'invention concerne des méthodes qui permettent fragmenter et/ou de marquer et/ou d'immobiliser des acides nucléiques consistant dans le marquage et/ou le clivage et/ou l'immobilisation au niveau des sites abasiques.

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