Methods for analyzing protein binding events

G - Physics – 01 – N

Patent

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Details

G01N 37/00 (2006.01) G01N 21/00 (2006.01) G01N 22/00 (2006.01) G01N 27/26 (2006.01) G01N 33/543 (2006.01)

Patent

CA 2378928

The present invention provides a variety of methods of analyzing protein binding events using a system capable of directly detecting protein/ligand complexes based upon the dielectric properties of the complex. The system can be used in a variety of analyses involving protein binding events, such as screening ligand libraries, characterizing protein binding interactions, and identifying ligands. The system can also be utilized in diverse analytical and diagnostic applications.

La présente invention concerne diverses méthodes d'analyse d'évènements de liaisons de protéines, à l'aide d'un système pouvant détecter directement des complexes protéine/ligand à partir des propriétés diélectriques du complexe. Ce système peut être utilisé dans diverses analyses associées à des évènements de liaisons de protéines, par exemple le criblage de bibliothèques de ligands, la caractérisation d'interactions de liaisons de protéines, et l'identification de ligands. Ce système peut également être utilisé dans diverses applications analytiques et diagnostiques.

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