Methods for characterizing molecular interactions using...

G - Physics – 01 – N

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G01N 33/68 (2006.01) H01J 49/00 (2006.01) H01J 49/42 (2006.01)

Patent

CA 2425434

The invention provides an analytical instrument comprising an affinity capture probe interface, a laser desorption ionization source, and a tandem mass spectrometer. Also presented are new methods for protein discovery and identification and for characterization of molecular interactions that utilize the instrument of the present invention.

L'invention concerne un instrument analytique comportant une interface sonde de capture par affinité, une source d'ionisation de désorption laser et un spectromètre de masse en tandem. Elle concerne également de nouveaux procédés permettant de découvrir et d'identifier des protéines, et de caractériser des interactions moléculaires utilisant ledit instrument.

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