Methods for controlling t lymphocyte mediated immune responses

Details Methods for controlling t lymphocyte mediated immune responses Methods for controlling t lymphocyte mediated immune responses

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01) C07K 7/04 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 14/765 (2006.01)

Patent

CA 2189425

Methods and compositions are provided for preventing the development of a T cell mediated autoimmune disease such as Type I diabetes, in which susceptible subjects have T cells sensitised to a disease-related antigen. Subjects are treated by administration of the antigen or fragments thereof to prevent the expansion of the population of sensitised T cells. Alternatively, subjects are treated by administration of immunogenic compositions comprising a mimicry antigen or fragments thereof.

Procédés et compositions servant à empêcher le développement d'une maladie auto-immune à médiation par lymphocytes T, par exemple le diabète de type I, dans laquelle les sujets sensibles ont des lymphocytes T sensibilisés à un antigène associé à la maladie. On traite les sujets par administration de l'antigène ou de ses fragments afin d'empêcher l'agrandissement de la population de lymphocytes T sensibilisés. Dans une variante, on traite les sujets par administration de compositions immunogènes comportant un antigène de mimétisme ou des fragments de celui-ci.

Affiliated with

Also associated with

Rating

Methods for controlling t lymphocyte mediated immune responses does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods for controlling t lymphocyte mediated immune responses, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods for controlling t lymphocyte mediated immune responses will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1999355