Methods for decreasing the frequency of transmission of...

Details Methods for decreasing the frequency of transmission of... Methods for decreasing the frequency of transmission of...

A - Human Necessities

61

K

A61K 31/717 (2006.01) A61K 9/10 (2006.01) A61K 9/14 (2006.01) A61P 15/00 (2006.01) A61P 31/04 (2006.01) A61P 31/18 (2006.01) A61P 31/22 (2006.01) A61K 47/30 (2006.01)

Patent

CA 2305331

A method for decreasing the frequency of transmission of human immunodeficiency virus or herpesviruses or for preventing the transmission of or treating a sexually transmitted bacteria] infection by administering to a human an anti-human immunodeficiency virus amount or an anti-herpesvirus amount or an anti-bacterial amount of cellulose acetate phthalate (CAP) or hydroxypropyl methylcellulose phthalate (HPMCP), such as in micronized form, or a combination thereof, either alone or in combination with a pharmaceutically acceptable carrier or diluent. The CAP and/or HPMCP may be employed as a suspension of micronized particles and may further contain a water miscible, non-solvent for CAP or HPMCP, such as glycerol.

L'invention concerne un procédé permettant de diminuer la fréquence de transmission du VIH et de l'herpèsvirus, ou bien de prévenir la transmission des infections bactériennes sexuellement transmissibles ou de traiter ces infections en administrant à un être humain une quantité anti-VIH ou anti-herpèsvirus ou une quantité antibactérienne d'acétophtalate de cellulose ou de phtalate d'hydroxypropylméthylcellulose, par exemple sous forme micronisée, ou bien une combinaison des deux, soit séparément soit en association avec un vecteur ou un diluant pharmaceutiquement acceptable. On peut utiliser l'acétophtalate de cellulose et/ou le phtalate d'hydroxypropylméthylcellulose sous forme de suspension de particules micronisées, et ces produits peuvent aussi renfermer un non solvant pour eux-mêmes, miscible avec l'eau, comme par exemple le glycérol.

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