Methods for delivering nucleic acid molecules into cells and...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/64 (2006.01) A61K 47/48 (2006.01) A61K 48/00 (2006.01) C12N 15/88 (2006.01)

Patent

CA 2495787

Methods for delivering nucleic acid molecules into cells and methods for measuring nucleic acid delivery into cells and the expression of the nucleic acids are provided. The methods are designed for introduction of large nucleic acid molecules, including artificial chromosomes, into cells.

L'invention concerne des procédés d'administration de molécules d'acides nucléiques dans des cellules et des procédés de mesure de l'administration d'acides nucléiques dans des cellules et de l'expression des acides nucléiques. Les procédés sont conçus pour l'introduction d'importantes molécules d'acides nucléiques, notamment des chromosomes artificiels, dans des cellules.

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