C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C07K 14/775 (2006.01) C07K 16/18 (2006.01) C07K 17/00 (2006.01) G01N 27/26 (2006.01) G01N 27/447 (2006.01) G01N 33/566 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2142300
Methods of diagnosing or prognosing Alzheimer's disease in a subject are disclosed. The method involves detecting the presence or absence of an apolipoprotein E type 4 (ApoE4) isoform or DNA encoding ApoE4 in the subject. The presence of ApoE4 indicates the subject is afflicted with Alzheimer's disease or at risk of developing Alzheimer's disease.
Enghild Jan
Roses Allen D.
Salvesen Guy S.
Schmechel Donald E.
Strittmatter Warren J.
Duke University
Sim & Mcburney
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