Methods for detecting and treating autoimmune disorders

A - Human Necessities – 61 – K

Patent

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A61K 39/395 (2006.01)

Patent

CA 2575604

The present disclosure relates to methods for inhibiting an autoimmune disease by administering to a subject a therapeutically effective amount of a composition that increases FOXP3 expression, thereby inhibiting the autoimmune disease. Further disclosed herein are methods for detecting in a subject an autoimmune disease or a predisposition to an autoimmune disease, and methods for assessing the efficacy of a therapy for an autoimmune disease.

L'invention concerne des procédés permettant d'inhiber une maladie auto-immune par administration à un patient d'une dose thérapeutiquement efficace d'une composition qui augmente l'expression de FOXP3, ce qui inhibe ladite maladie auto-immune. L'invention concerne en outre des procédés permettant de détecter chez un patient une maladie auto-immune ou une prédisposition à une telle maladie, ainsi que des procédés permettant d'évaluer l'efficacité d'une thérapie pour une maladie auto-immune.

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