Methods for detecting beta amyloid precursor protein...

Details Methods for detecting beta amyloid precursor protein... Methods for detecting beta amyloid precursor protein...

C - Chemistry, Metallurgy

12

Q

C12Q 1/37 (2006.01) A61K 31/445 (2006.01) A61K 31/655 (2006.01) A61K 38/08 (2006.01) A61K 38/55 (2006.01) C07K 14/47 (2006.01) C12N 9/64 (2006.01) G01N 33/561 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2095888

ABSTRACT Disclosed are methods for regulating formation of beta-amyloid protein with inhibitors of proteases specific for the Precursor to the Alzheimer's Disease beta-amyloid protein, such as inhibitors of aspartic protease, cathepsin D, and a chymotryptic-like serine protease; a method for detecting in vitro protease activity for molecules which possess specificity necessary for the degradation of the Amyloid Precursor Protein; and assays for identifying inhibitors of proteases specific for the Amyloid Precursor Protein. - 92 -

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