Methods for detecting for the presence of tumor cells and...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2409948

A method and kit for detecting the presence of tumor cells in an animal by detecting expression of VEGF-B186, determining an increased expression of VEGF- B186, or by determining an increased expression of VEGF-B186 relative to expression of VEGF-B167. The kit comprises a receptacle adapted to receive a sample and a means for detecting expression of VEGF-B186 from the sample. Also, a method for screening for anti-tumor agents.

L'invention concerne une méthode et un nécessaire servant à déceler la présence de cellules cancéreuses chez un animal. La méthode consiste à détecter l'expression de VEGF-B¿186?, à déterminer une expression accrue de VEGF-B¿186?, ou à déterminer une expression accrue de VEGF-B¿186? relativement à l'expression de VEGF-B¿167?. Le nécessaire comprend un réceptacle conçu pour recevoir un prélèvement, et un moyen servant à détecter l'expression de VEGF-B¿186? à partir dudit prélèvement. L'invention concerne en outre une méthode de criblage d'agents anticancéreux.

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