Methods for detecting genetic mosaicisms using arrays

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01)

Patent

CA 2461878

The invention provides array-based methods for determining genetic mosaicisms in cell populations, such as biopsy or body fluid samples or cultures of cancer cells. The invention also provides methods for optimizing performance of an array-based comparative genomic hybridization (CGH).

L'invention concerne des procédés basés sur des réseaux pour déterminer des mosaïcismes génétiques dans des populations cellulaires telles qu'une biopsie, des échantillons de fluides corporels ou des cultures de cellules cancéreuses. La présente invention porte également sur des procédés pour optimiser la performance d'une hybridation génomique comparative (CGH) basée sur des réseaux.

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