Methods for detecting or monitoring cancer using lpc as a...

Details Methods for detecting or monitoring cancer using lpc as a... Methods for detecting or monitoring cancer using lpc as a...

G - Physics

01

N

G01N 33/92 (2006.01) G01N 33/483 (2006.01)

Patent

CA 2705044

A method of detecting a cancer, such as ovarian cancer, in a test subject including (a) determining the amount of a lysophosphatidyl choline in a sample of a bodily fluid taken from the test subject, and (b) comparing the amount of the lysophosphatidyl choline in the sample of the bodily fluid taken from the test subject to a range of amounts of lysophosphatidyl choline found in samples of the bodily fluid taken from a group of normal subjects of the same species as the test subject and lacking the cancer, such as ovarian cancer, whereby a change in the amount of the lysophosphatidyl choline in the sample of the bodily fluid taken from the test subject indicates the presence of the cancer, such as ovarian cancer.

L'invention porte sur un procédé de détection d'un cancer, tel que le cancer des ovaires, dans un sujet de test, comprenant les opérations consistant à (a) déterminer la quantité d'une lysophosphatidyl choline dans un échantillon d'un fluide corporel prélevé à partir du sujet de test, et (b) comparer la quantité de la lysophosphatidyl choline dans l'échantillon du fluide corporel prélevé à partir du sujet de test à une plage de quantités de lysophosphatidyl choline trouvées dans des échantillons du fluide corporel prélevé à partir d'un groupe de sujets normaux de la même espèce que le sujet de test et n'étant pas atteints du cancer, tel que le cancer des ovaires, ce par quoi un changement de la quantité de la lysophosphatidyl choline dans l'échantillon du fluide corporel prélevé à partir du sujet de test indique la présence du cancer, tel que le cancer des ovaires.

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