Methods for detection and evaluation of bladder cancer

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 9/24 (2006.01) C07K 16/40 (2006.01) C12Q 1/02 (2006.01) C12Q 1/34 (2006.01) G01N 33/50 (2006.01) G01N 33/573 (2006.01) G01N 33/574 (2006.01) G01N 37/00 (2006.01)

Patent

CA 2242856

The present invention relates to novel methods for detecting and evaluating bladder cancer. The methods of the present invention are based on the discovery that normalized amounts of hyaluronic acid (HA) and hyaluronidase (HAase) are diagnostic markers for the detection of bladder cancer, evaluation of its grade, monitoring of the efficacy of its treatment, and tumor recurrence.

Cette invention a trait à de nouvelles techniques de détection et d'évaluation du cancer de la vessie. Les techniques selon cette invention se fondent sur la découverte que des quantités normalisées d'acide hyaluronique (HA) et d'hyaluronidase (Haase) constituent des marqueurs diagnostiques permettant de déceler un cancer de la vessie, d'évaluer son degré, de contrôler l'efficacité du traitement et de détecter une récurrence tumorale.

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