Methods for detection of carcinoma metastases by nucleic...

Details Methods for detection of carcinoma metastases by nucleic... Methods for detection of carcinoma metastases by nucleic...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C07H 21/04 (2006.01)

Patent

CA 2072314

Methods are provided for detecting carcinoma metastases in selected body tissue or fluid. These methods offer enhanced sensitivity compared to prior standard diagnostic methods. In one embodiment of the invention, target carcinoma associated nucleic acid sequences are identified for detecting minimal residual disease in lung carcinomas. The methods utilize nucleic acid amplification techniques, preferably, the polymerase chain reaction.

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