Methods for determining levels of human b-type natriuretic...

Details Methods for determining levels of human b-type natriuretic... Methods for determining levels of human b-type natriuretic...

G - Physics

01

N

G01N 33/68 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2482129

The present invention provides an alternate and more accurate assay for measuring the levels of BNP precursors, or fragments thereof, in a sample by determining the concentration of BNP precursors, or fragments thereof, in a sample obtained from a mammal, the method comprising treating the sample with an agent that cleaves the BNP precursor, and exposing the samplt to an antibody that specifically binds to the cleaved product.

L'invention concerne un test de remplacement plus précis de mesure de niveaux de précurseurs de BNP, ou de fragments de ces précurseurs, dans un échantillon, par détermination de la concentration de précurseurs de BNP, ou de fragments de ces précurseurs, dans un échantillon provenant d'un mammifère, le procédé consistant à traiter l'échantillon au moyen d un agent qui scinde le précurseur de BNP, et à exposer l'échantillon à un anticorps qui se lie spécifiquement au produit scindé.

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