C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2573590
A method for determining presence of lymphoma in a patient is disclosed. A sample of bone marrow, thymus, spleen, lymph nodes, lymph and/or lymphocytes taken from the patient t is assayed to determine expression of CDK9 and CYCLIN T1. The presence of CDK9 and/or CYCLIN T1 is indicative of a lymphoma other than a mantle cell lymphoma or marginal zone lymphoma in the patient.
L~invention concerne un procédé de détermination de la présence de lymphome chez un sujet. Un échantillon de la moelle osseuse, le thymus, la rate, ganglions lymphatiques, la lymphe et/ou les lymphocytes prélevés chez un patient t est analysé pour déterminer l~expression du CDK9 et de la CYCLINE T1. La présence du CDK9 et/ou de la CYCLINE T1 est indicatrice d~un lymphome autre que le lymphome à cellules du manteau ou le lymphome de la zone marginale chez le patient.
Giordano Antonio
Tosi Piero
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Sbarro Health Research Organization
Temple University
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