C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 38/00 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) C07H 21/04 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/82 (2006.01) C12N 5/00 (2006.01) C12N 5/02 (2006.01) C12N 15/10 (2006.01) C12P 19/34 (2006.01) C12P 21/04 (2006.01) C12Q 1/68 (2006.01) G01N 33/48 (2006.01) G01N 33/53 (2006.01) G01N 33/574 (2006.01)
Patent
CA 2334914
The invention relates to members of the SSX family of genes, as well as their uses. Also a part of the invention are peptides derived from SSX molecules and the NY-ESO-1 molecule, which form complexes with HLA molecules, leading to lysis of cells presenting these complexes, by cytolytic T cells.
Dans la présente invention, on divulgue des membres de la famille de gènes SSX, ainsi que leurs utilisations. On y divulgue également des peptides dérivés de molécules SSX et de la molécule NY-ESO-1, qui forment des complexes avec des molécules HLA, conduisant à la lyse de cellules présentant ces complexes par des cellules T cytolytiques.
Chen Yao-Tseng
Gure Ali
Old Lloyd J.
Pfreundschuh Michael
Rammensee Georg
Borden Ladner Gervais Llp
Cornell Research Foundation Inc.
Ludwig Institute For Cancer Research
Memorial Sloan Kettering Cancer Center
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