Methods for determining the influence of protein binding on...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/02 (2006.01) C12Q 1/18 (2006.01) C12Q 1/37 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2474671

The present invention relates to methods for determining the influence of human plasma or serum protein binding on antiretroviral activity at physiologically achieved conditions, by using specific virus strains in a cell- based antiviral assay.

L'invention concerne des procédés de détermination de l'influence du plasma ou la liaison de protéines sériques humains sur l'activité antirétrovirale dans des conditions physiologiquement acceptables, au moyen de souches de virus spécifiques dans un essai antiviral sur la base de cellules.

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