Methods for determining the potency, specificity, and...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/533 (2006.01) G01N 33/573 (2006.01) G01N 33/88 (2006.01)

Patent

CA 2575523

The present invention relates to a novel and useful method for assaying compounds and agents for their ability to decrease or inhibit the activity of hematopoietic prostaglandin D2 synthase (hPGDS). Specifically, the present invention relates to assays for measuring the potency, specificity and toxicity of hPGDS inhibitors.

La présente invention concerne une nouvelle méthode utile pour le dosage de composés et d'agents, en vue de déterminer leur capacité à diminuer ou inhiber l'activité de la prostaglandine D2 synthase hématopoïétique (hPGDS). Plus particulièrement, l'invention concerne des dosages servant à mesurer la puissance, la spécificité et la toxicité des inhibiteurs de la hPGDS.

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