Methods for determining the presence of brain protein s-100

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 14/47 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 16/18 (2006.01) G01N 33/53 (2006.01) G01N 33/543 (2006.01) G01N 33/574 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2259413

An assay method for determining the presence of the brain protein S-100 in a clinical sample which uses antibodies directed to epitopes in the region from ser1 to asn38 and from thr82 to glu93 of the amino acid sequence of the .beta. subunit of human S100B is provided.

L'invention concerne une méthode d'analyse permettant de déterminer la présence de la protéine cérébrale S-100 dans un échantillon clinique, qui fait appel à des anticorps dirigés contre les épitopes compris dans la région allant de ser1 à asn38 et de thr82 à glu93 de la séquence d'acides aminés de la sous-unité .beta. de la S-100B humaine.

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