Methods for diagnosing and treating diseases and conditions...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 31/00 (2006.01) A61K 31/70 (2006.01) A61K 31/7088 (2006.01) A61K 31/7105 (2006.01) A61K 38/17 (2006.01) A61K 45/00 (2006.01) A61K 48/00 (2006.01) A61P 1/00 (2006.01) A61P 1/04 (2006.01) A61P 1/16 (2006.01) A61P 1/18 (2006.01) A61P 35/00 (2006.01) A61P 43/00 (2006.01) C07H 21/04 (2006.01) C07K 14/46 (2006.01) C07K 16/00 (2006.01) C07K 16/18 (2006.01) C07K 16/26 (2006.01) C12N 1/15 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 9/00 (

Patent

CA 2460261

The invention provides methods of diagnosing and treating diseases and conditions of the heart or digestive system and cancer, methods for identifying compounds that can be used to treat or to prevent such diseases and conditions, and methods of using these compounds to treat or to prevent such diseases and conditions. Also provided in the invention are animal model systems that can be used in screening methods.

Méthodes de diagnostic et de traitement de maladies et d'états pathologiques touchant le coeur ou le système digestif, ainsi que du cancer, méthodes permettant d'identifier des composés qui peuvent être utilisés pour traiter ou prévenir ces maladies et états pathologiques, et méthodes d'utilisation desdits composés pour traiter ou prévenir ces maladies et états pathologiques. La présente invention concerne également des systèmes de modèles animaux qui peuvent être utilisés dans des méthodes de criblage.

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