C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2653071
The present invention relates to a method of diagnosis and/or prognosis of an inflammatory condition, which method comprises determining the expression level of TRIB1 in a biological sample of a patient, in particular in peripheral blood or in a biopsy of a diseased tissue. Methods for treating inflammatory conditions by modulating TRIB1 expression or activity are also described.
La présente invention concerne un procédé de diagnostic et/ou de pronostic d'une pathologie inflammatoire, le procédé consistant à déterminer le niveau d'expression de TRIB1 dans un échantillon biologique prélevé sur un patient, en particulier dans le sang périphérique ou dans la biopsie d'un tissu malade. L'invention concerne également des procédés destinés au traitement de pathologies inflammatoires par la modulation de l'expression ou de l'activité de TRIB1.
Ashton-Chess Joanna
Braud Christophe
Brouard Sophie
Soulillou Jean-Paul
Fetherstonhaugh & Co.
Inserm (institut National de La Sante Et de La Recherche Medical
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