C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) A61K 48/00 (2006.01) C07K 14/46 (2006.01) C12N 15/00 (2006.01)
Patent
CA 2396330
The invention provides methods of diagnosing heart disease, such as heart failure, screening methods for identifying compounds that can be used to treat or to prevent heart disease, and methods of using these compounds to treat or to prevent heart disease. The invention also provides animal model systems for carrying out the screening methods.
L'invention concerne des méthodes qui permettent de diagnostiquer et traiter une maladie du coeur telle que l'insuffisance cardiaque, des méthodes de sélection qui permettent d'identifier des composés pouvant être utilisés pour traiter ou prévenir une maladie du coeur, et des méthodes d'utilisation de ces composés pour traiter ou prévenir une maladie du coeur. L'invention concerne en outre des systèmes fondés sur le modèle animal destinés à mettre en oeuvre lesdites méthodes de sélection.
Fishman Mark C.
Xu Xiaolei
Smart & Biggar
The General Hospital Corporation
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