C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/28 (2006.01) A61K 38/17 (2006.01) A61K 38/34 (2006.01) A61P 3/04 (2006.01) A61P 5/06 (2006.01) G01N 33/53 (2006.01) G01N 33/566 (2006.01) C07K 14/72 (2006.01)
Patent
CA 2621950
Disclosed are biological markers for obesity and methods for diagnosing and treating obesity and related conditions by detecting and modulating the activity of auto-antibodies against the melanocortin-4 receptor or a portion of the melanocortin-4 receptor. Also disclosed are methods for discovering new therapeutics which modulate the activity of auto- antibodies against the melanocortin-4 receptor or a portion of the melanocortin-4 receptor, in particular which prevent the binding of auto-antibodies against the melanocortin-4 receptor or a portion of the melanocortin-4 receptor.
Hofbauer Karl
Jean-Christophe Peter
Gowling Lafleur Henderson Llp
University Of Basel
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