Methods for diagnosing and treating prostate and lung cancer

Details Methods for diagnosing and treating prostate and lung cancer Methods for diagnosing and treating prostate and lung cancer

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) G01N 33/543 (2006.01) G01N 33/574 (2006.01) C07K 14/705 (2006.01)

Patent

CA 2686954

Methods for detecting and treating prostate and lung cancer are disclosed. In practicing the method, a subject sample is assayed for GPR110 protein or its RNA transcript, and the GPR110 or transcript level observed is used in determining whether the subject has an elevated GPR110 level associated with prostate or lung cancer. Patients with such elevated levels may be treated, in accordance with the invention, with a variety of GPR110 related immunotherapy agents.

L'invention concerne des procédés pour détecter et traiter le cancer de la prostate et le cancer du poumon. Dans la mise en AEuvre du procédé, un échantillon du sujet est soumis à un essai pour la protéine GPR110 ou son transcrit d'ARN, et le taux de GPR110 ou de transcrit observé est utilisé pour déterminer si le sujet a un taux de GPR110 élevé associé à un cancer de la prostate ou du poumon. Des patients présentant de tels taux élevés peuvent être traités, conformément à l'invention, par une diversité d'agents d'immunothérapie apparentés à GPR110.

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