Methods for diagnosing and treating prostate cancer

Details Methods for diagnosing and treating prostate cancer Methods for diagnosing and treating prostate cancer

G - Physics

01

N

G01N 33/574 (2006.01) A61K 39/395 (2006.01) C07K 16/30 (2006.01)

Patent

CA 2640932

Methods for diagnosing and treating prostate cancer are disclosed. In practicing the method, a subject's body-fluid sample.is assayed for GPC3 protein, and the GPC3 level observed is used in determining whether the subject has an elevated GPC3 level associated with prostate cancer. Patients with such elevated levels may be treated, in accordance with the invention, with a variety of GPC3-related immunotherapy agents.

La présente invention concerne des procédés de diagnostic et de traitement du cancer de la prostate. Dans la mise en pratique du procédé, le taux de la protéine GPC3 est dosé dans un échantillon des liquides organiques d'un sujet et le taux de GPC3 observé est utilisé pour déterminer si le sujet présente un taux élevé de GPC3 associé au cancer de la prostate. Selon la présente invention, les patients qui présentent de tels taux élevés peuvent être traités avec divers agents immuno-thérapeutiques liés à la GPC3.

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