Methods for diagnosing htlv-i-mediated diseases

Details Methods for diagnosing htlv-i-mediated diseases Methods for diagnosing htlv-i-mediated diseases

G - Physics

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G01N 33/574 (2006.01) G01N 33/53 (2006.01) G01N 33/567 (2006.01)

Patent

CA 2485970

Protein biomarkers that may advantageously be utilized in aiding in, or making, a diagnosis of HTLV-I-associated myelopathy (HAM), adult T-cell leukemia (ATL) or a negative diagnosis are described. Accordingly, in one aspect of the invention, methods for aiding in, or otherwise making, a diagnosis of ATL, HAM or a negative diagnosis are provided. Methods of detecting the protein biomarkers, kits that may be utilized to detect the biomarkers, as well as isolated protein biomarkers are also provided.

La présente invention concerne des biomarqueurs protéiniques que l'on peut avantageusement utiliser pour faciliter ou poser le diagnostic d'une myélopathie ou d'une leucémie à cellules T de l'adulte associées à HTLV-1 ou pour poser un diagnostic négatif. L'invention se rapporte en conséquence, dans l'un de ses aspects, à des procédés permettant de faciliter, ou de poser, un diagnostic de myélopathie ou de leucémie à cellules T de l'adulte associées à HTLV-1, ou un diagnostic négatif. L'invention se rapporte enfin à des procédés de détection de biomarqueurs protéiniques, à des trousses qui peuvent être utilisées pour détecter lesdits biomarqueurs, et à des biomarqueurs protéiniques isolés.

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