Methods for diagnosing impending joint failure

Details Methods for diagnosing impending joint failure Methods for diagnosing impending joint failure

G - Physics

01

N

G01N 33/68 (2006.01) G06Q 50/22 (2012.01) G01N 35/00 (2006.01)

Patent

CA 2750608

The invention provides methods for diagnosing impending joint failure in an animal by measuring the concentra-tion of phenylalanine in a body fluid; measuring the concentration of one or more of tyrosine, alanine, valine, and glutamine in the body fluid; determining the ratio of phenylalanine to one or more of tyrosine, alanine, valine, and glutamine; and diagnosing im-pending joint failure by comparing the ratio to ratios predicative of impending joint failure.

La présente invention concerne des méthodes permettant de diagnostiquer un problème articulaire imminent chez un animal par la mesure de la concentration de la phénylalanine dans un fluide corporel ; par la mesure de la concentration d'un ou plusieurs acides aminés parmi la tyrosine, l'alanine, la valine, et la glutamine dans le fluide corporel ; par détermination du rapport entre la phénylalanine et un ou plusieurs acides aminés parmi la tyrosine, l'alanine, la valine, et la glutamine ; et le diagnostic d'un problème articulaire imminent par comparaison du rapport à des rapports prédictifs d'un problème articulaire imminent.

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