Methods for diagnosing pancreatic cancer using reg4 protein

G - Physics – 01 – N

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G01N 33/574 (2006.01) C07K 16/30 (2006.01)

Patent

CA 2645125

REG4, a new member of REG family was identified as a biomarker of pancreatic adenocarcinoma. The present invention provides sandwich ELISA to detect serum REG4 in patients with resectable pancreatic cancers i.e. PDACs. The present invention also provides a method for diagnosing a pancreatic cancer using REG4 as a serological marker.

La REG4, un nouveau membre de la famille REG, a été identifiée en tant que biomarqueur de l'adénocarcinome pancréatique. La présente invention concerne un test ELISA sandwich permettant de détecter la REG4 sérique chez des patients atteints de cancers du pancréas résécables, c'est-à-dire des adénocarcinomes ductaux pancréatiques. La présente invention concerne également un procédé de diagnostic d'un cancer du pancréas en utilisant la REG4 comme marqueur sérologique.

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