Methods for diagnosis and prognosis of skin cancer

G - Physics – 01 – N

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G01N 33/574 (2006.01) A61K 38/46 (2006.01)

Patent

CA 2731459

A method for diag-nosing an early stage melanoma which includes detecting the expres-sion level of dual specificity phos-phatase 1 protein (DUSP1) and a method for determining a prognosis for a subject having melanoma which includes detecting the expression lev-el of DUSP1 are disclosed. Also dis-closed are pharmaceutical composi-tions and kits comprised by these methods.

La présente invention concerne un procédé de diagnostic dun mélanome précoce qui comprend la détection du niveau dexpression de la protéine phosphatase 1 à double spécificité (DUSP1) et un procédé qui comprend la détermination dun pronostic pour un sujet ayant un mélanome qui comprend la détection du niveau dexpression de DUSP1. La présente invention concerne également des compositions pharmaceutiques et des kits compris par ces procédés.

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